Holistic security 4.0

The future computer climate will represent an ever more aligned world of integrating technologies, affecting consumer, business and industry sectors. The vision was first outlined in the Industry 4.0 conception. The elements which comprise smart systems or embedded devices have been investigated to determine the technological climate. The emerging technologies revolve around core concepts, and specifically in this project, the uses of Internet of Things (IoT), Industrial Internet of Things (IIoT) and Internet of Everything (IoE). The application of bare metal and logical technology qualities are put under the microscope to provide an effective blue print of the technological field. The systems and governance surrounding smart systems are also examined. Such an approach helps to explain the beneficial or negative elements of smart devices. Consequently, this ensures a comprehensive review of standards, laws, policy and guidance to enable security and cybersecurity of the 4.0 systems

Inhibition of Cancer Cell Migration by Multiwalled Carbon Nanotubes

Inhibiting cancer cell migration and infiltration to other tissues makes the difference between life and death. Multiwalled carbon nanotubes (MWCNTs) display intrinsic biomimetic properties with microtubules, severely interfering with the function of these protein filaments during cell proliferation, triggering cell death. Here it is shown MWCNTs disrupt the centrosomal microtubule cytoskeletal organization triggering potent antimigratory effects in different cancer cells

Polyspecificity of autoimmune responses in type 1 (autoimmune) diabetes

Autoimmunity is, by definition, supposed to be antigen specific [1], yet for almost 50 years, associations have been recognized between different autoimmune diseases [2–5]. For example, the increased incidence of gastric and thyroid autoimmunity in type 1 diabetes was first reported in 1963 [6]. These associations are in addition to the occasional cases of the autoimmune polyglandular syndromes [7] and are found independently of chronic mucocutaneous moniliasis, which is characteristic of the Type I syndrome (APECED), and Addison's disease which invariably occurs in the Type II syndrome [8]